(±)-2-(1H-Imidazole-1-yl)-2,4-dichloroacetophenone oxime

(±) -2 - (1H-imidazole-1-yl) -2,4-dichloroacetophenone oxime, an organic compound. Its chemical structure is quite unique and derived from the acetophenone skeleton.
Acetophenone part, introduced at the second position (1H-imidazole-1-yl), this imidazole group is a nitrogen-containing five-membered heterocycle, which has certain basicity and coordination ability, and can affect the chemical activity and physical properties of molecules. At the same time, when chlorine atoms are introduced at positions 2 and 4, the electronegativity of chlorine atoms is large, which can change the electron cloud density of the benzene ring, enhance the molecular polarity, and affect the properties of reactivity and solubility.
The oxime group is formed by the reaction of aldehyde or ketone with hydroxylamine. In this compound, the oxime group (= N-OH) is attached to the carbonyl carbon of acetophenone, which changes the carbonyl properties. Oxime compounds often have unique reactivity and can participate in a variety of organic synthesis reactions, such as Beckmann rearrangement.
As a whole ，（±） - the interaction of various parts in the structure of 2- (1H-imidazole-1-yl) -2,4-dichloroacetophenone oxime gives the compound unique physical and chemical properties, which may have potential applications in organic synthesis, medicinal chemistry and other fields.

(±) -2- (1H-imidazole-1-yl) -2,4-dichloroacetophenone oxime, this substance is widely used. In the field of medicine, it is often used as a key intermediate to help synthesize drugs with various effects such as antibacterial, anti-inflammatory and anti-tumor. Due to its special chemical structure, it can be tightly bound to specific biological targets, thus exhibiting good pharmacological activity. For example, when developing new antibacterial drugs, it can be used to modify the molecular structure of drugs and improve the inhibitory ability of drugs against pathogens.
In the field of pesticides, it also plays an important role. It can be used to create new pesticides with efficient pest control performance. By interfering with the physiological and metabolic processes of pests, it can effectively protect crops with relatively small impact on the environment, which is in line with the current needs of green agriculture development.
In the field of materials science ，（±） - 2- (1H-imidazole-1-yl) -2,4-dichloroacetophenone oxime is also used. It can be used as a functional additive to add to specific materials to enhance some properties of materials, such as improving material stability, oxidation resistance, etc., and then expand material application scenarios.
This compound has an indispensable position in many fields. With the continuous progress of science and technology, its potential uses may be further expanded and explored.

The synthesis of (±) -2 - (1H-imidazole-1-yl) -2,4-dichloroacetophenone oxime is an important research content in the field of organic synthesis. Its synthesis follows the following method.
First, 2,4-dichloroacetophenone is used as the starting material, and this compound is available in many chemical reagent supplies. Place 2,4-dichloroacetophenone in an appropriate reaction vessel, add an appropriate amount of solvent, such as ethanol, dichloromethane, etc., to fully dissolve the raw material to form a uniform reaction system.
Then, add imidazole. Imidazole, as a key reagent, undergoes a nucleophilic substitution reaction with 2,4-dichloroacetophenone. In order to make the reaction proceed smoothly, it is often necessary to add alkali substances, such as potassium carbonate, sodium carbonate, etc., to neutralize the acid generated during the reaction and promote the reaction forward. The reaction temperature is also very important. It is generally controlled in an appropriate range, such as between 50 and 80 ° C. The temperature can be precisely controlled by oil bath or water bath. At this temperature, the reaction takes several hours to fully react the raw materials.
After the initial completion of the reaction, the obtained mixture needs to be separated and purified. The commonly used method is extraction, with a suitable organic solvent, such as ethyl acetate, etc., to extract the reaction solution and transfer the target product to the organic phase. After that, the organic solvent is removed by distillation and other means to obtain the crude product.
The crude product needs to be further purified, and column chromatography can be used. Select a suitable silica gel as the stationary phase, and separate the crude product with a specific ratio of eluent, such as a mixture of petroleum ether and ethyl acetate. After this step, high purity (±) -2 - (1H-imidazole-1-yl) -2,4-dichloroacetophenone can be obtained.
Finally, the obtained (±) -2 - (1H-imidazole-1-yl) -2,4-dichloroacetophenone is reacted with hydroxylamine to generate (±) -2 - (1H-imidazole-1-yl) -2,4-dichloroacetophenone oxime. This reaction also requires appropriate reaction conditions, such as temperature and reaction time, to ensure the yield and purity of the product. After a series of reactions, separation and purification operations, the target product (±) -2 - (1H-imidazole-1-yl) -2,4-dichloroacetophenone oxime can be obtained.

(±) -2 - (1H-imidazole-1-yl) -2,4-dichloroacetophenone oxime is an organic compound. Its physicochemical properties are of great significance for chemical research and related fields.
The morphology of this compound is mostly solid at room temperature. Due to the arrangement of atoms and chemical bonds in the molecular structure, the intermolecular force prompts it to exist in the environment as a solid state. Its melting point is crucial for identification and purity detection. The purity of the compound can be determined by accurately measuring the melting point. If impurities are mixed in, the melting point often decreases or the melting range widens.
In terms of solubility ，（±） - 2- (1H-imidazole-1-yl) -2,4-dichloroacetophenone oxime exhibits a certain solubility in organic solvents such as ethanol and dichloromethane. This property is due to the combined action of lipophilic and hydrophilic groups in its molecular structure, which allows it to interact with specific organic solvent molecules and then dissolve.
From a chemical point of view, the imidazole group, chlorine atom and oxime group in its molecule are all active. Imidazolyl is rich in nitrogen atoms and has certain alkalinity. It can react with acids to form corresponding salts, and because of the lone pair of electrons on the nitrogen atom, it can participate in the coordination chemical process and form complexes with metal ions. The presence of dichloride atoms makes the compound nucleophilic substitution reactive. Under suitable conditions, chlorine atoms can be replaced by other nucleophilic reagents to derive a variety of compounds. Oxime groups can participate in a variety of organic reactions, such as Beckmann rearrangement reactions, etc., and can be converted into amide compounds, which greatly expands the application of this compound in the field of organic synthesis.
（±） - The unique physical and chemical properties of 2- (1H-imidazole-1-yl) -2,4-dichloroacetophenone oxime lay a solid foundation for its application in organic synthesis, medicinal chemistry and other fields.

(±) -2 - (1H-imidazole-1-yl) -2,4-dichloroacetophenone oxime, this substance is related to safety. Let me take the ancient Chinese saying of "Tiangong Kaiwu" as a gentleman.
Husband (±) -2 - (1H-imidazole-1-yl) -2,4-dichloroacetophenone oxime, among all things, its sex and safety are related to many things. However, everything in the world has its yin and yang sides, and this substance is no exception.
Look at its chemical structure, including imidazolyl and dichloroacetophenone oxime. These structures make it unique in chemical reactions. However, because of its chlorine content, chlorine is active, or makes this substance exhibit certain chemical activity in a specific environment.
Talk about safety, if it is not handled properly, or there are hidden dangers. In the storage environment, it is necessary to avoid water and fire. Because of its chemical activity, in case of hot topics and open flames, it is afraid of violent changes, damage to people and property. And it may have an impact on the environment. If it is accidentally released, it will enter the soil, water flow, or disturb the ecological balance.
And look at its impact on the human body, contact with this thing, or injury to the skin, mucous membranes, causing redness, swelling, and tingling. If inhaled, it will also damage the respiratory tract, causing people to cough and chest tightness.
Therefore, if you want to use this thing, you should be cautious. The operator must wear protective equipment, such as gloves and masks, to avoid the danger of contact and inhalation. Store the place, when strictly following the specifications, fireproof and waterproof, to keep it safe. In this way, (±) -2 - (1H-imidazole-1-base) -2,4-dichloroacetophenone oxime can be used in the right way without safety concerns.